Modulation of decompression sickness risk in pigs with caffeine during H2biochemical decompression
نویسندگان
چکیده
منابع مشابه
Modulation of decompression sickness risk in pigs with caffeine during H(2) biochemical decompression.
In H(2) biochemical decompression, H(2)-metabolizing intestinal microbes remove gas stored in tissues of animals breathing hyperbaric H(2), thereby reducing decompression sickness (DCS) risk. We hypothesized that increasing intestinal perfusion in pigs would increase the activity of intestinal Methanobrevibacter smithii, lowering DCS incidence further. Pigs (Sus scrofa, 17-23 kg, n = 20) that i...
متن کاملProbabilistic modelling for estimating gas kinetics and decompression sickness risk in pigs during H2 biochemical decompression.
We modelled the kinetics of H2 flux during gas uptake and elimination in conscious pigs exposed to hyperbaric H2. The model used a physiological description of gas flux fitted to the observed decompression sickness (DCS) incidence in two groups of pigs: untreated controls, and animals that had received intestinal injections of H2-metabolizing microbes that biochemically eliminated some of the H...
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A probabilistic model was used to predict decompression sickness (DCS) outcome in pig (70 and 20 kg), hamster (100 g), rat (220 g) and mouse (20 g) following air saturation dives. The data set included 179 pig, 200 hamster, 360 rat, and 224 mouse exposures to saturation pressures ranging from 1.9-15.2 ATA and with varying decompression rates (0.9-156 ATA • min-1). Single exponential kinetics de...
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BACKGROUND In a porcine model of neurological decompression sickness (DCS), perivascular leukocyte activation was a consistent finding in biopsies of associated cutaneous DCS. This prompted examination of other organs for similar changes; multifocal leukocyte activation was found in the lungs (pneumonitis) and liver (hepatitis). HYPOTHESIS DCS in pigs induces leukocyte aggregation and activat...
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Scuba diving is associated with an important risk of developing decompression sickness secondary to formation of gas bubbles inside the body. The latter is formed mainly by nitrogen in the body on the diver’s way to the surface (1,2). In some cases, it might injure the central nervous system. Several decompression cases that have been associated with neurologic symptoms are described in the l...
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ژورنال
عنوان ژورنال: Journal of Applied Physiology
سال: 2002
ISSN: 8750-7587,1522-1601
DOI: 10.1152/japplphysiol.00349.2002